Study of the Dynamics of Biofilm Formation and Elastase Activity of Pseudomonas aeruginosa in the Presence of Dodecanoyl-Homoserine Lactone
| Autor: | A. S. Dimova, N. A. Donchenko, T.E. Mironova, V. N. Afonyushkin, V. S. Cherepushkina, Ekaterina Nefedova, V. Yu. Koptev |
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| Rok vydání: | 2021 |
| Předmět: |
chemistry.chemical_classification
biology Chemistry Pseudomonas aeruginosa Elastase Homoserine Biofilm General Medicine medicine.disease_cause biology.organism_classification General Biochemistry Genetics and Molecular Biology Microbiology chemistry.chemical_compound medicine Lactone Bacteria Elastase activity |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 171:741-744 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-021-05307-z |
| Popis: | We studied the effect of early accumulation of N-3-oxo-dodecanoyl-homoserine lactone on the suppression of Pseudomonas aeruginosa reproduction, biofilm formation, and elastase activity. N-3-oxo-dodecanoyl-homoserine lactone in various concentrations was added to the P. aeruginosa culture, and changes in the concentration of bacteria and the formation of biofilms were studied in dynamics. N-3-oxo-dodecanoyl-homoserine lactone in a concentration of 25 μM, decelerated proliferation of bacterial cells during the first 6 h of culturing (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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