Beta-subunit of bovine rod photoreceptor cGMP phosphodiesterase. Comparison with the phosphodiesterase family

Autor:	Atabekova Nv, Valery M. Lipkin, K. J. Volpp, J. P. Johnston, Meredithe L. Applebury, K.G. Muradov, N.V. Khramtsov, T. Li, V.V. Gubanov, I. A. Vasilevskaya
Rok vydání:	1990
Předmět:	genetic structures biology Molecular mass Protein subunit Phosphodiesterase Cell Biology Biochemistry Molecular biology Complementary DNA biology.protein Genomic library sense organs PDE10A Beta (finance) Molecular Biology ATP synthase alpha/beta subunits
Zdroj:	Journal of Biological Chemistry. 265:12955-12959
ISSN:	0021-9258
DOI:	10.1016/s0021-9258(19)38252-3
Popis:	A group of cDNA clones encoding the beta-subunit of bovine rod photoreceptor cGMP phosphodiesterase were isolated for structural analysis. The encoded polypeptide has 853 residues with a calculated molecular mass of 98 kDa. The beta-subunit is 72% identical to the rod cGMP phosphodiesterase alpha-subunit. Like the alpha-subunit and the cone alpha'-subunit, the beta-subunit belongs to the family of phosphodiesterase genes. The beta- and alpha-subunits are more similar to each other than either is to the cone alpha'-subunit, suggesting either that the beta- and alpha-subunits diverged more recently or that their divergence was restrained by the rod functional environment.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::02b244dcfd9f50378c4aa03fadf559e3 https://doi.org/10.1016/s0021-9258(19)38252-3 Zobrazit plný text záznamu