The guanidine metabolites of Ptilocaulis spiculifer and related compounds; isolation and synthesis

Autor:	Patrick J. Murphy, Laura Heys, Christopher G. Moore
Rok vydání:	2000
Předmět:	chemistry.chemical_compound Sponge chemistry biology Biochemistry Ptilocaulis spiculifer Structural similarity Metabolite Organic chemistry Biological activity General Chemistry biology.organism_classification Guanidine
Zdroj:	Chemical Society Reviews. 29:57-67
ISSN:	1460-4744 0306-0012
DOI:	10.1039/a903712h
Popis:	Marine natural products possessing guanidine functionalities display a considerable array of biological activity and not surprisingly have attracted considerable synthetic interest. This review discusses the isolation of several guanidine containing metabolites, primarily from the sponge Ptilocaulis spiculifer, but also from other marine organisms. It also explores the synthetic methodologies adopted for their preparation and speculates on the structural similarity of the metabolite ptilomycalin A to abiotic guanidine based anionic receptor molecules.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::02a26ffe4795ae6f236065b7b4f50945 https://doi.org/10.1039/a903712h Zobrazit plný text záznamu