Asymmetric total synthesis of (−)-conduramine A-1 via a chiral syn,anti-oxazine

Autor:	Won-Hun Ham, In-Soo Myeong, Changyoung Jung, Yong-Taek Lee, Jin-Seok Kim, Jong-Cheol Kang, Seok-Hwi Park
Rok vydání:	2016
Předmět:	010405 organic chemistry Chemistry Stereochemistry Organic Chemistry Total synthesis 010402 general chemistry 01 natural sciences Catalysis 0104 chemical sciences Inorganic Chemistry Wittig reaction Salt metathesis reaction Stereoselectivity Physical and Theoretical Chemistry Chirality (chemistry)
Zdroj:	Tetrahedron: Asymmetry. 27:823-828
ISSN:	0957-4166
DOI:	10.1016/j.tetasy.2016.06.021
Popis:	The total synthesis of (−)-conduramine A-1 was achieved by using a diastereomerically enriched syn , anti -oxazine intermediate. The key steps in this strategy were the stereoselective extension of the chirality of syn , anti -oxazine, a Wittig reaction, and a ring-closing metathesis reaction.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::029fda1317645e7629b87e5919b260f8 https://doi.org/10.1016/j.tetasy.2016.06.021 Zobrazit plný text záznamu Full Text from ScienceDirect