Slow phosphor-Y-LAT-ion for TCR ligand discrimination

Autor:	Enrique Aguado, Mikel M Arbulo-Echevarria
Rok vydání:	2019
Předmět:	0301 basic medicine Ligand Chemistry Immunology Kinetics T-cell receptor Signal transducing adaptor protein chemical and pharmacologic phenomena Phosphor Tyrosine phosphorylation 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology 0302 clinical medicine Antigen Biophysics Immunology and Allergy Receptor 030215 immunology
Zdroj:	Nature Immunology. 20:1420-1422
ISSN:	1529-2916 1529-2908
DOI:	10.1038/s41590-019-0522-y
Popis:	A report sheds new light on the molecular mechanisms responsible for the discrimination of self versus non-self TCR ligands and reveals the crucial role of the kinetics of LAT tyrosine phosphorylation in this.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::029abbc7073f002f8ab2466d1ae6dbbd https://doi.org/10.1038/s41590-019-0522-y Zobrazit plný text záznamu Full text from SpringerLink