Antisense oligonucleotides targeting microRNA binding sites in the GRN mRNA increase progranulin translation: potential therapeutic strategy for frontotemporal dementia

Autor: Spencer Jones, Geetika Aggarwal, Yousri Benchaar, Jasmine Bélanger, Myriam Sévigny, Denise Smith, Michael Niehoff, Ian Mitchelle de Vera, Terri Petkau, Blair Leavitt, Karen Ling, Paymaan Jafar-Nejad, Frank Rigo, John Morley, Andrew Nguyen
Rok vydání: 2023
Zdroj: ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Neuropharmacology.
DOI: 10.1124/jpet.122.246730
Databáze: OpenAIRE