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Electrical impedance spirometry (EIS) is an effective method of bronchial constriction diagnosis and reflects first of all the airflow disturbances [1]. The study aims at comparison of electrical impedance airways properties evaluation using bronchodilatation test (BDT) in asthma and COPD patients. Material of investigation is presented by 20 patients with bronchial asthma (BA) and 20 ones with COPD. Spirometry tests were performed using Microlab equipment (Great Britain) and EIS - BIA-lab equipment (Perm, Russia) [1]. Nebulizer equipment was B. Well WN-116 U. Results. The coefficient of bronchodilation (BDC) was 26,4±3,43 in the group of BA and 11,2±1,19 % in COPD patients. We revealed strong decreasing of electrical impedance module |Z|. Mean values of this parameter were 32904,5±18786,47 before and 1558,2±14783,68 Ohm after BDT (p=0,0310). The depression of |Z| was deeper in the group of COPD patients than in asthmatics (p=0,0002). The deepest depression of |Z| was presented in those patients who had bronchiectasis which was confirmed by computer tomography. The degree of |Z| depression was strongly invert correlated with BDC in COPD patients (r=-0,7423, p=0,0158) and was not correlated in asthmatics. So we concluded that |Z| depression wasn9t connected with peak expiratory flow increasing during BDT and marked other mechanisms of bronchial obstruction (edema or mucous plugs). This suggestion is very realistic because |Z| dependence on geometry properties of ionic conductor is well known [2]. References Mishlanov V.Ju. et al. Russian J Physiol. n.a. I.M. Sechenov 2013; 99(12): 1425-1434. Apel P. Yu. et al. Petroleum Chemistry 2011, 51(7); 555-567. |
