High concentrations of CA 125 in uterine flushings: influence of cause of infertility and menstrual cycle day
| Autor: | Colin Wilson, J.A. Hamilton, Lionel K. Gunn, J.G. Grudzinskas, Ray K. Iles, A.M. Lower |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Infertility
medicine.medical_specialty business.industry Endocrinology Diabetes and Metabolism media_common.quotation_subject Serum protein Obstetrics and Gynecology Radioimmunoassay medicine.disease Peripheral blood Endocrinology Internal medicine Follicular phase medicine business Menstrual cycle Total protein media_common |
| Zdroj: | Gynecological Endocrinology. 16:19-25 |
| ISSN: | 1473-0766 0951-3590 |
| DOI: | 10.1080/gye.16.1.19.25 |
| Popis: | Uterine flushings were obtained under transvaginal ultrasonographic control from 132 women presenting for investigation and treatment of infertility. Levels of CA 125 were measured by radioimmunoassay and results expressed in relation to the total protein concentration of the same flushings. CA 125 was detected in uterine fluid at levels higher than those previously reported in peripheral blood. Uterine fluid CA 125 concentrations varied throughout the menstrual cycle, being highest in the mid-follicular phase (days 6 to 10). Uterine fluid CA 125 concentrations may reflect endometrial secretion of this protein more directly than serum levels. CA 125 concentrations did not vary according to the cause of infertility but further work in larger numbers of women is required. |
| Databáze: | OpenAIRE |
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