Fleroxacin in the Treatment of Chancroid: An Open Study in Men Seropositive or Seronegative for the Human Immunodeficiency Virus Type 1

Autor: Elizabeth Agoki, William Malisa, Frank Plummer, Mark W. Tyndall, Jackoniah O. Ndinya-Achola, Pierre J. Plourde, Allan R. Ronald
Rok vydání: 1993
Předmět:
Zdroj: The American Journal of Medicine. 94:85S-88S
ISSN: 0002-9343
DOI: 10.1016/s0002-9343(20)31144-x
Popis: Fleroxacin was prescribed to treat both HIV-negative and HIV-positive men with proven chancroid in an open study. HIV-negative men were treated with a single 400-mg dose of fleroxacin, and HIV-positive men were treated with 400 mg daily for 5 days. Three of the 58 evaluable HIV-negative men were clinical and microbiologic failures, and two of the 22 evaluable HIV-positive men had persisting infection with Haemophilus ducreyi. Both regimens were well tolerated. Fleroxacin is an acceptable alternative to existing treatment regimens for chancroid in men.
Databáze: OpenAIRE