Synthesis of azasugars. Part 1 isomerization of polyhydroxylated piperidines

Autor:	Jean-Claude Depezay, Yves Le Merrer, Lydie Poitout
Rok vydání:	1996
Předmět:	chemistry.chemical_compound Chemistry Stereochemistry Organic Chemistry Drug Discovery Iditol Biochemistry Isomerization
Zdroj:	Tetrahedron Letters. 37:1609-1612
ISSN:	0040-4039
Popis:	N- Benzyl -3,4- di -O- benzyl-1,5-dideoxy-1,5-imino- d -glucitol and l -gulitol undergo easy isomerization, mainly either by ring contraction, or either by SN 2 inversion at C2. This isomerization performed by bis-hydroxyl activation allows to access to 2,5-dideoxy-2,5-imino- l -iditol, 5-epi-DNJ, DMDP, and DMJ.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0238569dc5402e88de9827f1e930dd3e https://doi.org/10.1016/0040-4039(96)00096-2 Zobrazit plný text záznamu Full Text from ScienceDirect