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The cytotoxic dosage of exposed drug waste is frequently discharging on aquatic surfaces via wastewater treatment plants and pharma industries. Early detection of these drug wastes with a reliable and accurate are in great need. In this report, a noble metal effectively doped on oxidized one-dimensional (1D) single-walled carbon nanotube and abundant oxygen functional groups presenting two-dimensional (2D) graphene oxide on its surface, and hydrophobic cavities are the promising selector towards electrochemical oxidation of Naproxen (NPZ). A hybrid nanocomposite Au@f-CNT/GO was engineered by the ultrasound-assist sonication method and employed for the ultra-quantification of the therapeutic drug NPZ. In addition, various physicochemical and analytical techniques were utilized to confirm the successful formation of composite and principal detection of NPZ. Au@f-CNT/GO fabricated glassy carbon electrode exhibits a low resistance and higher electrocatalytic activity toward NPZ sensing. In addition, under the optimized condition, the sensor demonstrates an acceptable linear range of 100 nM − 15.6 µM, a lower limit of detection of 14 nM (S/N = 3), and higher sensitivity of 1.7484 μA μM−1 cm2. Furthermore, the proposed sensor has high selectivity, stability, reproducibility, and repeatability. Moreover, real sample analysis shows appreciable recovery results of 96 to 99% which strongly suggests that the proposed sensor has potential applicability for the sensitive detection of NPZ in the various water and biological samples. |
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