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Breast cancer is the most commonly diagnosed cancer in women and the leading cause of cancer death. About one million new cases are diagnosed each year in China [1]. According to the latest data released by the World Health Organization in 2017, the number of breast cancer deaths in China reached 49,011, accounting for 0.52% of the total deaths. The age-adjusted mortality rate is 5.76 deaths per 100,000 people, ranking China 179 globally. Worldwide, there will be an estimated 2.1 million newly diagnosed breast cancer cases for women in 2018, accounting for a quarter of all cancers in women. And there will be approximately 0.63 million breast cancer death in 2018 [2]. Recently, the incidence of this cancer is increasing in developing countries. Breast cancer is the most frequently diagnosed cancer in most countries (154 of 185 countries) and is also the leading cause of cancer deaths in more than 100 countries; the main exceptions are Australia/New Zealand, Northern Europe, North America (where lung cancer is the top one), and many countries in sub-Saharan Africa (due to the increased incidence of cervical cancer [2]). The incidence of breast cancer is the highest in countries such as Australia/New Zealand, Northern Europe (e.g., UK, Sweden, Finland, and Denmark), Western Europe (Belgium, Netherlands, and France), Southern Europe (Italy), and North America [2]. |
