Model-based analysis of a dielectrophoretic microfluidic device for field-flow fractionation
| Autor: | Mohammad Abutayeh, Anas Alazzam, Ion Stiharu, Bobby Mathew |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Field flow fractionation
Microchannel Steady state Materials science Physics::Medical Physics 010401 analytical chemistry Analytical chemistry Equations of motion Filtration and Separation 02 engineering and technology Mechanics Dielectrophoresis 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Analytical Chemistry Volumetric flow rate Physics::Fluid Dynamics Physics::Plasma Physics Drag Levitation 0210 nano-technology |
| Zdroj: | Journal of Separation Science. 39:3028-3036 |
| ISSN: | 1615-9306 |
| DOI: | 10.1002/jssc.201600350 |
| Popis: | We present the development of a dynamic model for predicting the trajectory of microparticles in microfluidic devices, employing dielectrophoresis, for Hyperlayer field-flow fractionation. The electrode configuration is such that multiple finite-sized electrodes are located on the top and bottom walls of the microchannel; the electrodes on the walls are aligned with each other. The electric potential inside the microchannel is described using the Laplace equation while the microparticles' trajectory is described using equations based on Newton's second law. All equations are solved using finite difference method. The equations of motion account for forces including inertia, buoyancy, drag, gravity, virtual mass, and dielectrophoresis. The model is used for parametric study; the geometric parameters analyzed include microparticle radius, microchannel depth, and electrode/spacing lengths while volumetric flow rate and actuation voltage are the two operating parameters considered in the study. The trajectory of microparticles is composed of transient and steady state phases; the trajectory is influenced by all parameters. Microparticle radius and volumetric flow rate, above the threshold, do not influence the steady state levitation height; microparticle levitation is not possible below the threshold of the volumetric flow rate. Microchannel depth, electrode/spacing lengths, and actuation voltage influence the steady-state levitation height. |
| Databáze: | OpenAIRE |
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