In vivo 31P nuclear magnetic resonance spectroscopy of bone mineral for evaluation of osteoporosis

Autor:	Jeffrey P Moore, R Srinivasan, Peter Sigmann, J R Allaway, J H Battocletti, C E Brown
Rok vydání:	1988
Předmět:	Bone mineral Bone disease business.industry Chemistry Biochemistry (medical) Clinical Biochemistry Osteoporosis Soft tissue Nuclear magnetic resonance spectroscopy Wrist medicine.disease medicine.anatomical_structure Nuclear magnetic resonance In vivo medicine Spectroscopy Nuclear medicine business
Zdroj:	Clinical Chemistry. 34:1431-1438
ISSN:	1530-8561 0009-9147
Popis:	The mineral content of stationary bone samples can be quantified by 31P nuclear magnetic resonance (NMR) spectroscopy. The assay can be performed in regions of the anatomy that pose problems for absorptiometric techniques, because the mineral content is measured within a selected volume without concern for the geometry of the bone. In vivo 31P NMR spectra of the bones in human fingers and wrist are reported. Soft tissue such as marrow and skeletal muscle contributes little to the 31P NMR spectra of human fingers and wrist and thus should not seriously affect the accuracy of the mineral assay. 31P NMR spectrometry should prove helpful for confirming rapid bone mineral loss in those at risk and for monitoring response to treatment.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::01f8fc1c694853aaa9fc886ef465d7dd https://doi.org/10.1093/clinchem/34.7.1431 Zobrazit plný text záznamu