Total and regional bone mass and biochemical markers of bone remodeling in metastatic prostate cancer
| Autor: | H. Rico, M. Sanchez-Chapado, I. Arribas, L.F. Villa, M. Revilla, F. Bethencourt |
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| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
Osteolysis biology medicine.diagnostic_test business.industry Urology Acid phosphatase medicine.disease Bone resorption Metastasis Bone remodeling Prostate cancer Endocrinology medicine.anatomical_structure Oncology Prostate Internal medicine medicine biology.protein business Dual-energy X-ray absorptiometry |
| Zdroj: | The Prostate. 35:243-247 |
| ISSN: | 1097-0045 0270-4137 |
| Popis: | BACKGROUND The osteolytic activity of metastases of prostate cancer was evaluted in relation to total body bone mineral content (TBBMC) and regional bone mineral content (RBMC). METHODS Bone mass was determined by dual-energy X-ray absorptiometry (DXA). Tartrate-resistant acid phosphatase (TRAP) was measured as a biochemical marker of bone resorption. RESULTS In 32 patients (mean age 72 ± 4 years) compared with 32 controls (mean age 73 ± 5 years), there were significant differences in TRAP (P < 0.0001), TBBMC (P < 0.0001), and RBMC in the pelvis (P < 0.0001), legs (P = 0.0001), and trunk (P |
| Databáze: | OpenAIRE |
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