Association of Polymorphisms of Chicken Adipose Differentiation-related Protein Gene with Carcass Traits

Autor:	Huarui Du, Xiaosong Jiang, Xiaoling Zhao, Qing Zhu, Yi-Ping Liu
Rok vydání:	2009
Předmět:	Genetics Linkage disequilibrium medicine.medical_specialty Haplotype Adipose tissue Single-nucleotide polymorphism Quantitative trait locus Biology medicine.disease Major gene Obesity Exon Endocrinology Internal medicine medicine Animal Science and Zoology
Zdroj:	The Journal of Poultry Science. 46:87-94
ISSN:	1349-0486 1346-7395
Popis:	Adipose differentiation-related protein (ADFP) plays an important role in regulating lipid storage and affecting body fat distribution. The objective of the current research was to identify the polymorphisms in chicken ADFP gene and their associations with carcass traits. We screened all coding sequence and part of introns (totally 2155bp) of the ADFP gene by using single strand conformation polymorphism method in individuals from Sanhuang chicken, Mountainous Black-bone chicken and a commercial crossbred chicken (totally 427 birds). Three novel single-nucleotide polymorphisms were found in intron 4 (SNP1), intron 5 (SNP2) and exon 8 (SNP3), respectively. The association analyses showed that genotypes of SNP1 were significantly associated with abdominal fat weight and percentage of abdominal fat (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::01dda3b6981242e7614d6de7765fa482 https://doi.org/10.2141/jpsa.46.87 Zobrazit plný text záznamu