667 Effects of Sleep-Extend on glucose metabolism in women with a history of gestational diabetes: A pilot study

Autor:	Kelly Glazer Baron, Pamela Martyn-Nemeth, Sirimon Reutrakul, Brett Rydzon, Laurie Quinn, Jennifer Duffecy, Kirstie K. Danielson
Rok vydání:	2021
Předmět:	Fitness Trackers Pediatrics medicine.medical_specialty business.industry Actigraphy Carbohydrate metabolism medicine.disease Sleep in non-human animals Gestational diabetes Physiology (medical) medicine Anxiety Neurology (clinical) medicine.symptom Self report business Postpartum period
Zdroj:	Sleep. 44:A261-A261
ISSN:	1550-9109 0161-8105
DOI:	10.1093/sleep/zsab072.665
Popis:	Introduction Experimental and epidemiological data have linked insufficient sleep to increased diabetes risk. Women with a history of gestational diabetes (GDM) have a 7-fold greater risk of developing type 2 diabetes. This pilot study explored the feasibility of a sleep extension intervention in women with a history of GDM and short sleep, and the effects on glucose metabolism. Methods Women age 18–45 years with a history of GDM (at least 1 year postpartum) and actigraphy confirmed short sleep duration ( Results Twelve women (mean (SD) age 40.3 (4.5) years) participated (n=8 Sleep Extend, n=4 control). Compared to baseline, nightly sleep duration increased in Sleep Extend group (+30.6 (48.8) minutes) but decreased in the control group (-6.8 (22.9) minutes). Both fasting and 2-h glucose levels from OGTT increased in both groups but were greater in the control group (Sleep extend vs. healthy living: fasting glucose +2.1 (9.8) vs. +12.8 (7.3) mg/dL; 2-h glucose +8.2 (21.9) vs. +20.0 (19.4) mg/dL). Self-reported sleep quality improved in both groups. When compared controls, Sleep Extend participants reported improved fatigue symptoms (Promis fatigue score change -5.1 (9.3) vs. 7.0 (1.0), p=0.008), and self-reported physical activity tended to increase (+1614 (3659) vs. -2900 (3922) MET-minutes/week). Combining all participants, an increase in sleep duration correlated with a decrease in fatigue (r= -.62, p=0.04) and anxiety symptoms (r= -.69, p=0.02). Conclusion Sleep extension through coaching and use of remote monitoring is feasible in women with a history of GDM. It appears to decrease fatigue and may improve glucose metabolism and physical activity. Support (if any) NIDDK P30 DK092949
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::01c23a0917533d4581f12da626aa82ad https://doi.org/10.1093/sleep/zsab072.665 Zobrazit plný text záznamu