| Popis: |
Purpose: To compare the effectiveness of transcatheter arterial chemoembolization combined with microwave ablation (TACE-MWA) versus repeated hepatic resection (RHR) among patients with recurrent small hepatocellular carcinoma (sHCC) after primary resection. Materials and Methods: A total of 59 patients with recurrent sHCC (size ≤ 3cm) treated by TACE-MWA or RHR were collected from two centers between June 2015 and October 2021. Patients who were treated by either TACE-MWA or RHR were matched by propensity score at 1:1 ratio. Disease-free survival (DFS), overall survival (OS) and complications were compared between groups. Results: A total of 38 patients were enrolled in this study after matching, with 19 patients in each group. Before matching, the corresponding 1-, 3-, and 5-year DFS rates were 68.1%, 46.6%, and 23.3% for the TACE-MWA group, and 84.6%, 47.3%, and 47.3% for the RHR group. The 1-, 3-, and 5-year OS rates were 100.0%, 83.7%, and 47.8% for the TACE-MWA group, and 100.0%, 95.0%, and 45.2% for the RHR group, respectively. After matching, the corresponding 1-, 3-, and 5-year DFS rates were 78.0%, 48.3%, and 24.1% for the TACE-MWA group, and 77.5%, 38.7%, and 38.7% for the RHR group. The 1-, 3-, and 5-year OS rates were 100.0%, 88.9%, and 54.9% for the TACE-MWA group, and 100.0%, 93.3%, and 44.4% for the RHR group, respectively. No statistically significant difference was found in either DFS rates or OS rates between groups before matching (P=0.825 and P=0.625) and after matching (P=0.834 and P=0.490). Conclusions: Compared with RHR, TACE-MWA could provide equivalent effectiveness for recurrent sHCC. |
