Do Different Proportions of Antibiotics in the CTZ Paste Interfere with the Antimicrobial Action? In Vitro Study
| Autor: | Gerana Araujo de Lucena Lira, Suzana Cavalcanti Monteiro de Oliveira, José Carlos Pettorossi Imparato, Ivana Aguiar Ferreira, Ana Luiza Costa Silva de Omena, Ana Flávia Bissoto Calvo |
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| Rok vydání: | 2019 |
| Předmět: |
food.ingredient
biology medicine.drug_class Tetracycline Chloramphenicol Chlorhexidine Antibiotics biology.organism_classification Enterococcus faecalis Eugenol chemistry.chemical_compound food chemistry Pediatrics Perinatology and Child Health medicine Agar Food science Candida albicans General Dentistry medicine.drug |
| Zdroj: | Pesquisa Brasileira em Odontopediatria e Clínica Integrada. 19:1-8 |
| ISSN: | 1983-4632 1519-0501 |
| DOI: | 10.4034/pboci.2019.191.115 |
| Popis: | Objective: To evaluate the antimicrobial action of the CTZ paste in three different proportions by diffusion in agar with the microorganisms: Enterococcus faecalis , Escherichia coli , and Candida albicans . Material and Methods: Three different proportions of antibiotics were tested: GROUP A - CTZ paste in the ratio of 33.33% chloramphenicol + 33.33% tetracycline + 33.33% zinc oxide, mixed with 2 drops of eugenol (1:1:1 ratio); GROUP B - CTZ paste in the proportion of 25% chloramphenicol + 25% tetracycline + 50% zinc oxide, mixed with 2 drops of eugenol (1: 1: 2 ratio); GROUP C - CTZ paste with 13% chloramphenicol + 13% tetracycline + 74% Zinc Oxide, mixed with 2 drops of eugenol (1:1:6 ratio); PC GROUP - Positive Control (0.12% Chlorhexidine); and NC GROUP - Negative Control (0.9% Saline solution). Data were analyzed through descriptive statistics (means and standard deviation). The one-way ANOVA and Tukey’s test were used, with a significance level of 5%. Results: No statistical differences for Enterococcus faecalis between groups A, B, and C (p = 0.1986) were found. There were statistical differences for Escherichia coli between groups B and C (p = 0.029), and for Candida albicans between groups A and C (p = 0.006). Groups A, B, and C had significant differences with both Positive and Negative Controls for all the microorganisms . Conclusion: The three different ratios of CTZ paste showed antimicrobial efficacy against Enterococcus faecalis , Escherichia coli, and Candida albicans microorganisms. |
| Databáze: | OpenAIRE |
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