Discovery of novel sesquiterpenoids from a gorgonian Menella sp

Autor:	Jui-Hsin Su, Wei-Hsien Wang, Chan-Shing Lin, Ping-Jyun Sung, Shih-Yao Kao, Lee-Shing Fang, Yin-Di Su, Jyh-Horng Sheu, Yu-Chia Chang, Tsong-Long Hwang
Rok vydání:	2011
Předmět:	Chloranthalactone B biology Superoxide Stereochemistry Metabolite Organic Chemistry Carbon skeleton biology.organism_classification Sesquiterpene Biochemistry Terpenoid chemistry.chemical_compound Gorgonian chemistry Drug Discovery Enantiomer
Zdroj:	Tetrahedron. 67:7311-7315
ISSN:	0040-4020
DOI:	10.1016/j.tet.2011.07.043
Popis:	A novel sesquiterpenoid, menelloide A ( 1 ), which was found to possess a new carbon skeleton, and a new guaiane-type sesquiterpenoid, menelloide B ( 2 ), along with (+)-chloranthalactone B ( 3 ), an enantiomer of the known sesquiterpenoid, chloranthalactone B ( 4 ), were isolated from a gorgonian coral identified as Menella sp. The structures of sesquiterpenoids 1 – 3 were established by spectroscopic methods and by comparison of the data with those of related metabolites. Sesquiterpenoids 1 and 3 displayed inhibitory effects on the generation of superoxide anion by human neutrophils.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::019d2feabd44775b67ffad445c052721 https://doi.org/10.1016/j.tet.2011.07.043 Zobrazit plný text záznamu Full Text from ScienceDirect