PATTERNS OF PRESCRIPTION AND ANTIBIOTIC USE AMONG OUTPATIENTS IN A TERTIARY CARE TEACHING HOSPITAL OF BANGLADESH
| Autor: | M. Ashraf Ali, Bytul M. Rahman, Sumon Kumar Datta, Ambia Khatun, Monalisa Monwar, Mir Imam Ibne Wahed, Ranjan Kumar Barman, M. Rafiqul Islam, Tripti Rani Paul |
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| Rok vydání: | 2016 |
| Předmět: |
Pharmacology
Drug Polypharmacy medicine.medical_specialty Pediatrics business.industry medicine.drug_class media_common.quotation_subject Antibiotics Pharmaceutical Science Guideline Drug resistance 030226 pharmacology & pharmacy Tertiary care 03 medical and health sciences 0302 clinical medicine Internal medicine Medicine 030212 general & internal medicine Medical prescription Antibiotic use business media_common |
| Zdroj: | International Journal of Pharmacy and Pharmaceutical Sciences. 8:60 |
| ISSN: | 0975-1491 |
| DOI: | 10.22159/ijpps.2016v8i11.9827 |
| Popis: | Objective: Irrational drug use increased the risk of adverse drug reactions (ADRs), the emergence of drug resistance and a leading cause of morbidity and mortality worldwide. The study was designed to analyse prescription patterns and antibiotic use among outpatients in a tertiary care teaching hospital in Bangladesh.Methods: This prospective survey was conducted among the out-patients in a district hospital. The prescribed drugs were classified according to Anatomical and Therapeutic Chemical (ATC) classification system. Patient characteristics and drug data were recorded. The prescription pattern was analysed using general drug use indicators according to world health organisation (WHO).Results: A total of 405 prescriptions were analyzed of which 54% of child and 46% of adult prescriptions. The age and body weight of the patients were not mentioned in 30% of child and 62% of adult prescriptions and none of the prescriptions included sex of the patients. Physician’s handwriting was not clear and legible in 31% prescriptions. A total 1362 drugs were used in this study with an average 3.36 drugs per prescription. However, none of the drugs was prescribed in generic name. Children were highly exposed to antibiotics (66%) than to adults (44%) of which cephalosporin’s (30%) and macrolides (14%) were commonly used. Interestingly, non-steroidal anti-inflammatory drugs (NSAIDs) were also highly accounted in children (53%) than to adults (36%).Conclusion: Our results suggested that the prescription information was incomplete and physicians did not follow the standard guideline for drug treatment resulting in polypharmacy and indiscriminate use of antimicrobials irrespective to the age of patients. |
| Databáze: | OpenAIRE |
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