Assessment of Haematological Parameters in Drug-Resistant TB
| Autor: | null Abdulrazzaq Neamah Zghair |
|---|---|
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Journal of Techniques. 5:137-143 |
| ISSN: | 2708-8383 1818-653X |
| DOI: | 10.51173/jt.v5i1.1082 |
| Popis: | Mycobacterium tuberculosis causes tuberculosis (TB), the world's deadliest infectious illness. In addition to the lungs, bone marrow is also impacted by tuberculosis. Significant haematological abnormalities can be found in TB patients. This means that these haematological markers can be used to assess a patient's diagnosis, prognosis, and treatment outcome. The goals of this study are (a) to assess the hematological characteristics of TB patients, and (b) to examine the impact of rifampin (RIF) resistance on the prevalence of mutations in the whole rpoB gene of Mycobacterium tuberculosis. Fifty people participated in the study after being chosen through a systematic random sample process. From each participant, about 4 milliliters of blood were taken from a vein and estimated for the haematological parameters like Hb, WBC, Lymphocyes, neutrophils, Erythrocyte sedimentation rate and platelet count. Fifty tuberculosis isolates had their whole rpoB genes sequenced so that we could analyze the positions of the codons and the frequency with which they occurred. When compared to healthy controls, the values of hemoglobin and other blood indices were significantly lower or abnormal (p |
| Databáze: | OpenAIRE |
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