Autor:	N. V. Kovganko, V. L. Survilo
Rok vydání:	2002
Předmět:	Hydroxylation chemistry.chemical_compound chemistry Dehydrohalogenation Organic chemistry Cholestane Plant Science General Chemistry General Biochemistry Genetics and Molecular Biology
Zdroj:	Chemistry of Natural Compounds. 38:257-263
ISSN:	0009-3130
Popis:	3β-Chloro-5α,7α-dibromo-6-ketosteroids 5a and 5b are synthesized from β-sitosterol (1a) and cholesterol (1b). Dehydrohalogenation of these forms 7α-bromo-2,4-dien-6-ones (6a-b), 2,4-dien-6-ones (7a-b), and 14α-hydroperoxy-2,4,7-trien-6-ones (8a-b). Woodward hydroxylation of dienone 6a produces 2β-iodo-7α-bromo-3α-acetoxy-Δ4-6-ketone 9 and 7α-bromo-2α,3α-diacetoxy-Δ4-6-ketone 10. 2β-Iodo-3α-acetoxy-Δ4,7,14-trien-6-one 11 is prepared analogously from trienone 8a.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::01775420c1eb8706b3969b42e1ca9ff7 https://doi.org/10.1023/a:1020432027888 Zobrazit plný text záznamu Full text from SpringerLink