Detection of acalculous gallbladder disease using Tc99m EHIDA imaging and cholecystokinin

Autor: J. H. Williams, G. W. Middleton
Rok vydání: 1994
Předmět:
Zdroj: European Radiology. 4:462-463
ISSN: 1432-1084
0938-7994
DOI: 10.1007/bf00212822
Popis: The use of Tc99m ethyl hepatic iminodiacetic acid (EHIDA) imaging with cholecystokinin (CCK) in a prospective study of 115 patients with right upper quadrant biliary-type pain is described. All patients had normal US, oral cholecystography and/or endoscopy investigations. A 2-min infusion of CCK was administered at peak gallbladder uptake of EHIDA. A gallbladder ejection fraction (CBEF) was used to quantify the gallbladder response to CCK. A total of 79 of 115 patients (69%) had an abnormal GBEF (≤ 35%). Of 43 patients who underwent cholecystectomy 42 (97%) had abnormal surgical/histological findings and/or complete long-term relief of symptoms. It was concluded that Tc99m EHIDA imaging, with a 2-min infusion of CCK and a measured GBEF ≤ 35%, is highly predictive of acalculous gallbladder disease and a favourable outcome following cholecystectomy.
Databáze: OpenAIRE