Increase associated risk of gynaecological cancer due to long-term exposure to high concentration of atmospheric SO2 industrial pollutant
| Autor: | Qian Xu, Lanqin Cao, Chan Lu, Rachael Gakii Murithi |
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| Rok vydání: | 2021 |
| Předmět: |
Pollutant
High concentration business.industry Public Health Environmental and Occupational Health Building and Construction 010501 environmental sciences Gynaecological cancer 01 natural sciences Term (time) 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Environmental health Cohort Medicine business 0105 earth and related environmental sciences |
| Zdroj: | Indoor and Built Environment. 31:2183-2192 |
| ISSN: | 1423-0070 1420-326X |
| Popis: | A cohort case–control study was conducted in XiangYa Hospital, Changsha, China, which involved 305 patients and 399 healthy women, from June 2010 to December 2018, to evaluate the association between Chinese women’s short- and long-term exposure to industrial air pollutant, SO2 and gynaecological cancer (GC). We obtained personal and family information from the XiangYa Hospital electronic computer medical records. Using data obtained from the air quality monitoring stations in Changsha, we estimated each woman’s exposure to the industrial air pollutant, sulphur dioxide (SO2), for different time windows, including the past 1, 5, 10 and 15 years before diagnosis of the disease. A multiple logistic regression model was used to assess the association between GC and SO2 exposure. GC was significantly associated with long-term SO2 exposure, with adjusted odds ratio (95% confidence interval) = 1.56 (1.10–2.21) and 1.81 (1.07–3.06) for a per interquartile range increase in the past 10 and 15 years, respectively. Sensitivity analysis showed that different groups reacted in different ways to long-term SO2 exposure. We concluded that long-term exposure to high concentration of industrial pollutant, SO2 is associated with the development of GC. This finding has implications for the prevention and reduction of GC. |
| Databáze: | OpenAIRE |
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