Dual reactivity of 1-chloro- and 1-bromo-3,5-dinitrobenzenes in aromatic nucleophilic substitution
| Autor: | Olga V. Serushkina, Egor S. Bobrov, Evgeniya V. Kolvina, Mikhail D. Dutov, Svyatoslav A. Shevelev, Vladimir N. Koshelev, David R. Aleksanyan, Olga D. Neverova |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Substitution reaction
Radical-nucleophilic aromatic substitution 010405 organic chemistry Chemistry General Chemistry 010402 general chemistry 01 natural sciences Medicinal chemistry 0104 chemical sciences Nucleophile Nucleophilic aromatic substitution Halogen Nucleophilic substitution Organic chemistry Reactivity (chemistry) Lewis acids and bases |
| Zdroj: | Mendeleev Communications. 27:160-162 |
| ISSN: | 0959-9436 |
| DOI: | 10.1016/j.mencom.2017.03.018 |
| Popis: | Aromatic nucleophilic substitution reactions in 1-halo-3,5-dinitrobenzenes (where the halogen is bromine or chlorine) can occur with replacement of either a nitro group or a halogen atom, depending on the nature of anionic nucleophile Nu– as a Lewis base (hard, soft or intermediate), as well as on the polarity of the dipolar aprotic solvent. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect