'B' cell origin of malignant cells in a case of american burkitt's lymphomacharacterization of cells from a pleural effusion
Autor: | Byungkyu Chun, Richard A. Binder, Judith A. Jencks, Charles E. Rath |
---|---|
Rok vydání: | 1975 |
Předmět: | |
Zdroj: | Cancer. 36:161-168 |
ISSN: | 1097-0142 0008-543X |
DOI: | 10.1002/1097-0142(197507)36:1<161::aid-cncr2820360114>3.0.co;2-p |
Popis: | Ninety-eight percent of the cells isolated from a malignant pleural effusion in a case of American Burkitt's lymphoma showed membrane fluorescence to antihuman IgM antisera, while only 2% of the cells formed spontaneous rosettes with sheep red blood cells. It is concluded that the Burkitt cells in the malignant effusion are derived from bursal equivalent lymphocytes. Epstein-Barr (E-B) viral titers to both viral capsule antigen and early antigen were not elevated. The significance of these findings is discussed. |
Databáze: | OpenAIRE |
Externí odkaz: |