Antiviral Properties of the New Coordination Compound Silver Bis(Citrato)Germanate

Autor:	I. I. Seifullina, Elena Chebanenko, Elena Martsinko, T. L. Gridina, A. Fedchuk, L. M. Mudrik
Rok vydání:	2019
Předmět:	Pharmacology chemistry.chemical_classification Oseltamivir 010405 organic chemistry Human influenza Coordination polymer viruses Pharmacology toxicology virus diseases Reference drug 01 natural sciences Medicinal chemistry Effective dose (pharmacology) respiratory tract diseases 0104 chemical sciences Coordination complex 010404 medicinal & biomolecular chemistry chemistry.chemical_compound chemistry Drug Discovery Germanate
Zdroj:	Pharmaceutical Chemistry Journal. 53:318-321
ISSN:	1573-9031 0091-150X
DOI:	10.1007/s11094-019-01999-w
Popis:	The new coordination polymer silver bis(citrato)germanate was synthesized and exhibited pronounced antiviral activity against human influenza virus strains A/Hong Kong/1/68 (H3N2) and A/Puerto Rico/34 (H1N1). Its effective dose was five times lower than that of the reference drug oseltamivir, which made this compound promising for further studies in animal models.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::01297f95c3b76cb64f36d68ba2cf2c8e https://doi.org/10.1007/s11094-019-01999-w Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.