Adult Onset Immunodeficiency Associated with Anti-interferon Gamma Autoantibodies

Autor: Wannada Laisuan, Nizchapa Dechapaphapeaktak, Supa Oncham, Porntip Intapiboon, Chamard Wongsa, Ticha Rerkpattanapipat, Malinee Tongdee, Thanuchporn Kafaksom
Rok vydání: 2017
Předmět:
Zdroj: The Bangkok Medical Journal. 13:87-94
ISSN: 2287-0237
2228-9674
DOI: 10.31524/bkkmedj.2017.02.015
Popis: Adult onset immunodeficiency associated with anti-interferon-gamma autoantibodiesis an emerging medical issue worldwide especially in South-east Asia. Most patientspresent with disseminated non-tuberculous mycobacteria (NTM) infection and otheropportunistic infections. In addition to standard antimicrobial therapy, immunomodulatoror immunosuppressive drug seem to play a role in some cases. In the present study, we thoroughly reviewed the pathogenesis, clinical features,laboratory diagnosis, modalities of treatment, and clinical outcomes of this condition.
Databáze: OpenAIRE