Primary peritoneal carcinoma: a rare neoplasm with pleomorphic trophoblastic morphology
| Autor: | Charlotte Winther Madsen, Lise Grupe Larsen, Jane Preuss Hasselby |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Microbiology (medical)
Pathology medicine.medical_specialty Gestational trophoblastic disease General Medicine Biology medicine.disease Pathology and Forensic Medicine Human chorionic gonadotropin Primary peritoneal carcinoma medicine.anatomical_structure Peritoneum medicine Carcinoma Mitotic Figure Immunology and Allergy Neoplasm Immunohistochemistry |
| Zdroj: | APMIS. 114:574-579 |
| ISSN: | 1600-0463 0903-4641 |
| DOI: | 10.1111/j.1600-0463.2006.apm_293.x |
| Popis: | We report a case of primary peritoneal carcinoma with trophoblastic morphology in a 78-year-old woman, diagnosed by histological and immunohistochemical analysis of surgically resected specimens, including the omentum and part of the small bowel. Microscopically, the resected specimens showed diffuse infiltration of a poorly differentiated tumor. Numerous large, often multinucleated cells were seen, and mitotic figures were frequent. Immunohistochemical staining showed a positive reaction for most cytokeratins, EP4, EMA, CA-125, Glut1, WT1, β-hCG and PLAP. We reached a diagnosis of primary peritoneal carcinoma with trophoblastic morphology. To our knowledge this morphology of a primary peritoneal carcinoma has not been described previously. |
| Databáze: | OpenAIRE |
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