Adjuvant Therapy for Stage III Melanoma Without Immediate Completion Lymph Node Dissection

Autor: Laura D. Leonard, Rene Gonzalez, William A. Robinson, Chloe Friedman, Karl D. Lewis, Theresa Medina, Felix Ho, Ana Gleisner, Camille L. Stewart, Daniel Thieu, Robert J. Torphy, Nicole Kounalakis, Martin D. McCarter
Rok vydání: 2021
Předmět:
Zdroj: Annals of Surgical Oncology. 29:806-815
ISSN: 1534-4681
1068-9265
Popis: For patients with stage III melanoma with occult lymph node metastasis, the use of adjuvant therapy is increasing, and completion lymph node dissection (CLND) is decreasing. We sought to evaluate the use of modern adjuvant therapy and outcomes for patients with stage III melanoma who did not undergo CLND. Patients with a positive SLNB from 2015 to 2020 who did not undergo CLND were evaluated retrospectively. Nodal recurrence, recurrence-free survival (RFS), distant metastasis-free survival (DMFS), and melanoma-specific survival were evaluated. Among 90 patients, 56 (62%) received adjuvant therapy and 34 (38%) underwent observation alone. Patients who received adjuvant therapy were younger (mean age: 53 vs. 65, p
Databáze: OpenAIRE