A new preparative method for the synthesis of diethyl 1-diazo-2,2,2-trifluoroethylphosphonate via an imino phosphonate

Autor:	N. M. Karimova, Sergey N. Osipov, G. T. Shchetnikov, D. V. Vorobyeva
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Carbamate Imidoyl chloride Chemistry medicine.medical_treatment medicine Organic chemistry Diazo General Chemistry Isopropyl nitrite Trifluoroacetic anhydride Phosphonate
Zdroj:	Russian Chemical Bulletin. 59:107-109
ISSN:	1573-9171 1066-5285
Popis:	A preparative method for the synthesis of diethyl 1-diazo-2,2,2-trifluoroethylphosphonate from trifluoroacetic anhydride and benzyl carbamate via diethyl 1-benzyloxycarbonylimino-2,2,2-trifluoroethylphosphonate is developed. Optimum conditions for the chlorination of benzyl N-trifluoroacetylcarbamate with SOCl2—Py to afford the imidoyl chloride, phosphorylation of the latter under the conditions of the Arbuzov reaction, as well as diazotization of amino phosphonate with isopropyl nitrite are found.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::00a98793d4f5fbdd1b56a5f413297929 https://doi.org/10.1007/s11172-010-0051-1 Zobrazit plný text záznamu Full text from SpringerLink