Preimplantation Genetic Testing: A Review of Past and Current

Autor: Aisha Elaimi
Rok vydání: 2021
Předmět:
Zdroj: Asian Journal of Biochemistry, Genetics and Molecular Biology. :78-85
ISSN: 2582-3698
DOI: 10.9734/ajbgmb/2021/v10i130230
Popis: The field of medical genetics has seen significant and incredible advances in technology for the past several decades. Genetic technologies, particularly in the reproductive medicine discipline, represent a fresh era in medicine that may develop significantly in the coming years. The purpose of Preimplantation Genetic Testing (PGT) in the situation of assisted reproductive technology (ART) treatments with IVF (in vitro fertilization) or ICSI (intracytoplasmic sperm injection) is particularly controversial as it is done before implantation [1]. However, despite the successful application of PGT in the field of IVF in overcoming infertility and genetic defects, the techniques pose various limitations, and concerns that need to be addressed to enhance their success rate [2]. This review will introduce PGT and summarize the molecular techniques used in its application as well as highlight the future advances in the field.
Databáze: OpenAIRE