Intradiscal Steroids
| Autor: | Sara J. Kimmich, J. N. McMillin, S. F. Emery, James W. Simmons |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Sciatica
Bupivacaine medicine.medical_specialty Visual analogue scale business.industry Methylprednisolone acetate Low back pain Surgery law.invention Intervertebral disk Randomized controlled trial law Anesthesia medicine Back pain Orthopedics and Sports Medicine Neurology (clinical) medicine.symptom business medicine.drug |
| Zdroj: | Spine. 17:S172-S175 |
| ISSN: | 0362-2436 |
| DOI: | 10.1097/00007632-199206001-00019 |
| Popis: | A prospective, randomized, double-blind study was performed to evaluate the clinical efficacy of intradiscal steroid injections. Criteria for entrance were one-level internal disc disruption or nonsequestered nuclear prolapse with or without sciatica and a positive pain response on awake discography. Exclusion criteria were multilevel disease, central or lateral stenosis, prior lumbar surgery, or medical disease requiring systemic steroids. A total of 25 patients were randomly assigned to Treatment Group A (methylprednisolone, Depo-Medrol 80 mg/ml, The Upjohn Co., Kalamazoo, Michigan) or Treatment Group B (bupivacaine, Marcaine .5% 1.5 ml, Sanofi Winthrop Pharmaceuticals, New York, New York). Fourteen patients received Depo-Medrol, with 21% showing subjective improvement and 79% no improvement; 0% were clinically worse. Eleven patients received intradiscal Marcaine, with 9% showing clinical improvement and 91% no improvement; 0% were clinically worse. To quantify clinical response, a pain diagram grid score, a visual analog scale, and the Oswestry Pain Questionnaire were used before injection and 10-14 days after injection. No statistically significant benefit was identified in the use of intradiscal steroids. |
| Databáze: | OpenAIRE |
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