A Methodological Review of the Royal College of General Practitioners' Oral Contraception Study

Autor: J. I. Galbraith
Rok vydání: 1998
Předmět:
Zdroj: Journal of Nutritional & Environmental Medicine. 8:187-194
ISSN: 1364-6907
1359-0847
DOI: 10.1080/13590849862221
Popis: The Royal College of General Practitioners' Oral Contraception Study, started in 1968/9, is reviewed. The limitations of any cohort study and the particular characteristics of this study mean that only large effects on common diseases are likely to be detected. Effects on conditions that might be subject to reporting bias, and on those, like cancers, which may only appear after a long time lag, are particularly unlikely to be estimated with any accuracy. The study does show a clear connection between oral contraceptive use and cardiovascular disease. It also suggests a range of conditions, including depression and some cancers, whose incidence might be increased by oral contraceptive use, and a few whose incidence might be decreased.
Databáze: OpenAIRE
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