| Popis: |
Introduction: Small intestine, the longest part of digestive tract, makes up about 75% of the total length and can be affected by various developmental, inflammatory or neoplastic conditions. Non neoplastic lesions like abdominal tuberculosis are frequently seen in small intestine. Although small intestine is an uncommon site for tumour nearly twothirds of these tumours are malignant, with most of them being adenocarcinoma. To study the histopat Objective: hology of various neoplastic and non-neoplastic lesions of small intestine and to evaluate their frequency and pattern with respect to age, sex, anatomical sites and clinical findings. This observational cross-sectional Materials and Methods: study was conducted on a total of 101 small intestinal specimens including biopsies and surgically resected specimen received for histopathological examination over a period of two years in the Department of Pathology affiliated with tertiary care hospital. In addition to Haematoxylin and Eosin staining, Immunohistochemistry and special stains were also done in required cases. This study showed a male is to female ratio of 1.97:1. Peak incidence of Results: cases was seen in the 31-40 years age group. Out of total 101 pathological lesions 87 cases were non -neoplastic that included Infective lesions like tuberculous enteritis, Inflammatory lesions like Non-specific Enteritis, Necrotising Enteritis and Congenital lesions like Meckel's diverticulum, Enteric Duplication cyst and Celiac disease while only 14 cases were neoplastic that included benign neoplastic lesions like various types of polyps and malignant neoplastic lesions like adenocarcinoma, GIST, neuroendocrine tumour and B cell NHL. This study showed a characteristic Conclusion: distribution of cases in the three different parts of small intestine and highlighted the clinical importance of timely detection of intestinal pathology by the means of detailed clinical study combined with radiological and histopathological examination. |
