Antibacterial cuminaldehyde/hydroxypropyl-β-cyclodextrin inclusion complex electrospun fibers mat: Fabrication and characterization
| Autor: | Mohammad Mahdi Hajjari, Niloufar Sharif, Mohammad-Taghi Golmakani, Elham Aghaee, Jahan B. Ghasemi |
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| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
Materials science Polymers and Plastics Scanning electron microscope technology industry and agriculture Infrared spectroscopy Electrospinning Biomaterials chemistry.chemical_compound chemistry Chemical engineering Proton NMR Cuminaldehyde Molecule Thermal stability Safety Risk Reliability and Quality Antibacterial activity Food Science |
| Zdroj: | Food Packaging and Shelf Life. 29:100738 |
| ISSN: | 2214-2894 |
| DOI: | 10.1016/j.fpsl.2021.100738 |
| Popis: | Electrospinning process has been applied to fabricate hydroxypropyl-β-cyclodextrin fibers mat incorporating of cuminaldehyde. The inclusion complex formation between cuminaldehyde and hydroxypropyl-β-cyclodextrin was proved by computational molecular docking. The proton nuclear magnetic resonance results revealed that cuminaldehyde was present in final inclusion complex at 0.92:1 molecular ratio. Moreover, the presence of cuminaldehyde in the electrospun fibers in the inclusion state along with the host hydroxypropyl-β-cyclodextrin molecules was proved by Fourier-transform infrared spectroscopy. The results of scanning electron microscopy and confocal Raman spectroscopy revealed the formation of uniform fiber morphology with average fibers diameter of 381 ± 178 nm. The thermal stability of cuminaldehyde was improved after electrospinning process. Finally, the promising antibacterial activity of fibers against Escherichia coli and Staphylococcus aureus confirmed the suitability of electrospinning process for the developing cuminaldehyde-loaded fibers with potential application in food area such as active packaging structures. |
| Databáze: | OpenAIRE |
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