Can neutrophil-to-lymphocyte ratio be used as a predictor in acute appendicitis?
| Autor: | Leo Francis Tauro, Rohan D'Souza, Manohar Martis, Chirag Pereira |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Receiver operating characteristic analysis business.industry Abdominal ultrasound fungi Ultrasound Critical Care and Intensive Care Medicine medicine.disease Appendix Appendicitis medicine.anatomical_structure Acute appendicitis Emergency Medicine Medicine Histopathology Radiology Neutrophil to lymphocyte ratio business |
| Zdroj: | Journal of Emergency Medicine, Trauma and Acute Care. 2021 |
| ISSN: | 1999-7094 1999-7086 |
| DOI: | 10.5339/jemtac.2021.6 |
| Popis: | Background: To determine if neutrophil-to-lymphocyte ratio (NLR) can be used to diagnose appendicitis and distinguish complicated from uncomplicated appendicitis. The secondary aim was to determine if the appendix cut-off size on ultrasound matches that of existing literature. Methods: We retrospectively analyzed all cases that underwent appendectomy in Father Muller medical college and hospital from 2014 to 2019. The NLR, histopathology, and ultrasound reports for all patients were reviewed. Recommended cut-off values for NLR and appendicular size on ultrasound were determined using receiver operating characteristic analysis (ROC). Data was analyzed using SPSS version 25. Ethical approval was obtained for this study. Results: We included 1623 patients in this study. The patients’ median age was 24 years, with appendicitis being more common in males than females. NLR>2.4 was statistically associated with appendicitis with sensitivity of 70.1% and specificity of 43.2%. NLR>4.3 was statistically associated with complicated appendicitis with sensitivity of 72.25% and specificity of 54.09%. An appendicular diameter >6.1 mm was suggestive of appendicitis on abdominal ultrasound based on our analysis. Conclusions: NLR is a simple adjunct that can be used to diagnose appendicitis and identify complicated appendicitis. |
| Databáze: | OpenAIRE |
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