High-performance microcalorimeters: Design, applications and future development
| Autor: | Xiaocheng Liu, Honglong Chang, Jianguo Feng, Vojtěch Svatoš, Pavel Neužil |
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| Rok vydání: | 2018 |
| Předmět: |
Materials science
business.industry 010401 analytical chemistry 02 engineering and technology Integrated circuit design 021001 nanoscience & nanotechnology Chip 01 natural sciences Temperature measurement Fluid handling 0104 chemical sciences Analytical Chemistry Biochemical reactions 0210 nano-technology Process engineering business Spectroscopy |
| Zdroj: | TrAC Trends in Analytical Chemistry. 109:43-49 |
| ISSN: | 0165-9936 |
| Popis: | Microcalorimetry has been widely used to measure and characterize the heat change in phase transition, resolution mixing, and chemical/biochemical reactions. In this review, we discuss progress in the development of high-performance microfabricated calorimeters starting with their design, fluid handling, and temperature measurement. The considerations of chip design are highlighted. Then, a few representative applications are introduced and their chip parameters and properties are compared. Finally, trends and prospects of microcalorimeters for high-performance applications, such as enthalpy measurements in minute volumes of chemicals suitable for drug discovery as well as bio-applications in energy balance monitoring of living cells and investigation of their thermogenesis, are discussed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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