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Purpose To compare the doses calculated from the measurements of the tumour obtained by different imaging techniques. Methods It is a retrospective study of 50 enucleated eyes corresponding to 50 patients with diagnosis of choroidal melanoma. For every case, there was recorded information about height of the tumour obtained by means of studies of pathological anatomy both in the macroscopic and in the microscopic preparation, and the obtained with the available imaging techniques for this measurement: magnetic nuclear resonance RNM, computerized tomography CT and B ultrasound US. Dose distribution was calculated in the tumour apex by means of the brachytherapy treatments planning system Bebig for three applicators type COMS of three and all slots filled for a duration of treatment of 1 hour, and was analyzed later by a spreadsheet Excel and the statistical application SPSS. Results Apex dose differences (%) Comparison with the macroscopic preparation Applicator size 10 mm 16 mm 22 mm CT 16,5 14,8 13,4 MNR 3,6 4,9 5,5 US 6,0 7,3 5,0 Conclusion Obtained results can be influenced partly by the size of the studied tumours, in the main of big size, and for the small muestral size in someone of the imaging techniques. They show the importance of the election of the imaging technique to obtain the information for dosimetry. Particularly relevant they are the obtained ones in the comparison with the CT due to the difficulty for this technology of distinguishing between the tumour and the detachment of retina associated. Acknowledgments: This work has been financed partly by a grant of the Junta de Castilla y Leon (Order SAN/1829/2007 of November 13, BOCYL of November 15, 2007) |
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