Bone and Joint Involvement in Celiac Disease
| Autor: | Marie Sedláčková, Lenka Franeková |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Lactose intolerance biology business.industry Tissue transglutaminase HLA-DQ2 food and beverages nutritional and metabolic diseases medicine.disease Gluten Gastroenterology digestive system diseases Sprue chemistry Internal medicine biology.protein Medicine Enteropathy business Gliadin Irritable bowel syndrome |
| Zdroj: | Gerontorheumatology ISBN: 9783319311678 |
| DOI: | 10.1007/978-3-319-31169-2_22 |
| Popis: | Celiac disease (celiac sprue, gluten-sensitive enteropathy) is a chronic inflammatory condition that primarily affects the small intestine mucosa and is clinically manifested by bowel symptoms of various severities. However, it may have also a number of extraintestinal manifestations which prevail in adulthood, and as a result the disease goes unnoticed. Celiac disease is an autoimmune condition induced by gliadin fraction of gluten, protein that can be found in grains such as wheat, rye, barley, and oat, in genetically predisposed individuals – HLA DQ2 or DQ8 carriers [3, 11, 17]. |
| Databáze: | OpenAIRE |
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