| Autor: |
Yan-mei XIA, Hai-peng SHI, Wei-dong WU, Xiu-zhe WANG |
| Jazyk: |
čínština |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Medical Journal of Chinese People's Liberation Army, Vol 44, Iss 7, Pp 605-610 (2019) |
| ISSN: |
0577-7402 |
| Popis: |
Objective To investigate the effect of urinary neutrophil gelatinase-associated lipocalin (uNGAL) on the timing of continuous renal replacement therapy (CRRT) in patients with acute renal injury (AKI) associated with sepsis. Methods One hundred patients with sepsis admitted to Shanxi Grand Hospital from January 2013 to June 2017 were selected as research objects. Sixty patients with uNGAL greater than 1310 ng/ml were defined as high uNGAL group, and 40 patients with uNGAL smaller than 1310 ng/ml were defined as low uNGAL group. The high uNGAL group was randomly assigned to the early CRRT group or standard treatment group. The clinical outcomes were compared between the high uNGAL group and the low uNGAL group. Changes in the levels of uNGAL, TNF-α and IL-6 inflammatory factors at different time points before and after treatment in the early CRRT group and the standard treatment group. Results The 28 d mortality and dialysis dependence rate in the high uNGAL group were significantly higher than those in the low uNGAL group (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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