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Background: strenuous training-induced reactive oxygen species is associated with several chronic diseases by damaging cell proteins and membrane lipids; it seems uric acid as a major intracellular antioxidant could lower membranous lipid peroxidation and muscle damage. The aim of this study was to examine the effect of six weeks of high-intensity interval training with and without zinc on serum Creatine Kinase and uric acid in female futsal players. Methods: Thirty-two female futsal players were randomly divided into four groups: placebo, Zinc, HIT and Zinc+HIT. All subjects had to attend futsal-specific training three sessions per week. Zinc and Placebo groups took 30 mg day−1 of zinc gluconate or dextrose, respectively; HIT groups accomplished high-intensity interval training contained 6 to 10 repetitions of a 30-second running at 100% of VO2peak with a 4-minutes rest between efforts, during six weeks. Results: After six weeks, Creatine Kinase levels augmented insignificantly from 83.98 to 120.19 (P=0.101) in placebo, from 99.58 to 150.1(P=0.167) in HIT and from 81.07 to 107.90 (P=0.152) in HIT+Zinc group; while Creatine Kinase levels increased significantly from 66.86 to 124.81(P=0.004) only in Zinc group. Uric acid levels increased in all groups (Placebo (P=1), Zinc (P=0.317), HIT (P=0.157), Zinc+HIT (P=1)) insignificantly Conclusions: The findings indicated that after six weeks, serum Creatine Kinase and uric acid levels increased insignificantly in all groups; Creatine Kinase levels augmented significantly, only in Zinc group. Zinc as an antioxidant supplement could not decrease the muscle damage, and even increased the serum Creatine Kinase as a marker of muscle damage, significantly |
