DEVELOPMENT OF TECHNOLOGIES AND PHARMACO-TECHNOLOGICAL RESEARCH COMBINED ANTIHYPERTENSIVE NEW TABLETS

Autor: Strelnikov L.S., Trutaev I. V., Strilets O. P.
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Anali Mečnikìvsʹkogo Institutu, Vol 3, Pp 24-27 (2013)
ISSN: 1993-4327
Popis: The new original drug, code-named "Bisopamid" in theform of tablets, are proposed for the treatment ofhypertension. As active ingredients of the tablets areantihypertensive substances from differentpharmacological groups, namely bisoprolol fumarate(beta-blocker), lisinopril dihydrate (ACE inhibitor), andindapamide (thiazide diuretic). Tablets "Bisopamid"using excipients (lactose monohydrate, potato starch,MCC, calcium stearate) were obtained by directcompression. The main pharmaco-technologicalcharacteristics of the developed tablets "Bisopamid" wereconducted and there were found that all the investigatedtechnological characteristics meet the requirements ofHFCs.
Databáze: OpenAIRE