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Changsheng Yan,1 Yi Jiang,1 Yicong Wan,1 Lin Zhang,2 Jinhui Liu,1 Shulin Zhou,1 Wenjun Cheng1 1Department of Gynecology, The First Affiliated Hospital of Nanjing Medical University, 2Department of Obstetrics and Gynecology, Zhongda Hospital Affiliated to Southeast University, Medical School, Southeast University, Nanjing, Jiangsu, People’s Republic of China Abstract: Long noncoding RNA (lncRNA) has been proven to be involved in many biological processes in ovarian cancer (OC). However, the mechanism still remains unknown. In this study, we screened significantly downregulated NBAT-1, which has been proven to play a significant role in breast cancer, clear cell renal cell carcinoma, and neuroblastoma, but not in OC, in two independent datasets with relatively more samples (GSE18520 and GSE38666) from Gene Expression Omnibus. We found that lncRNA NBAT-1 was obviously downregulated in OC tissue compared to normal ovarian tissue (P |
