| Autor: |
Xue - Fang Chen, Zhong - Xin Liu, Bing - Rong Chen, Liu Ping, Zheng Yi |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Guoji Yanke Zazhi, Vol 13, Iss 6, Pp 1073-1076 (2013) |
| ISSN: |
1672-5123 |
| Popis: |
AIM: To investigate the protective effect of resveratrol on human lens epithelial cells against ultraviolet-induced apoptosis. METHODS:Subcultured human lens epithelial cell line, ultraviolet induced cell apoptosis, 20μmol/L resveratrol pretreated cell, the indicators change was observed: rate of apoptosis was detected by flow cytometry and apoptosis-related factors of caspses-3 and caspase-9 were detected by colorimetric detection, ultrastructure changes were observed under transmission electron microscope. RESULTS: Flow cytometry instrument testing found that resveratrol can suppress the apoptosis induced by ultraviolet irradiation, caspses-3 and caspase-9 content in positive control group were significantly higher than that of the negative control group at the same time period, the difference was statistically significant(P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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