| Autor: |
José Ignacio BENITO-OREJAS, Fernando BENITO-GONZÁLEZ, Fernando GARCÍA-VICARIO, Gerardo MARTÍN-SIGÜENZA, María REY-MARCOS, María Luisa SERRANO-MADRID, Elisa GIL-CARCEDO-SAÑUDO, Jesús SAN-ROMÁN-CARBAJO, Laura CURIESES-BECERRIL, Victor Manuel MARUGÁN-ISABEL |
| Jazyk: |
Spanish; Castilian |
| Rok vydání: |
2019 |
| Předmět: |
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| Zdroj: |
Revista ORL, Vol 10, Iss 4, Pp 253-261 (2019) |
| ISSN: |
2444-7986 |
| Popis: |
Introduction: Given the importance of early antiviral treatment in infants with sensorineural hearing loss secondary to congenital cytomegalovirus infection (cCMV), we submit a protocol for early diagnosis of cCMV according to the outcome of universal newborn hearing screening using automated auditory brainstem responses (AABR) (targeted CMV screening). Material and methods: Based on current knowledge provides by literature, we elaborate an action algorithm agreed between the coordinators of the Early Hearing Detection and Intervention program in Castilla y León (Spain). Results: If the first AABR test is a refer result for one or both ears, we request the identification of the viral genome by PCR in a urine sample within 15 days. The confirmation of uni or bilateral sensorineural hearing loss, allows the beginning of the antiviral treatment, before the first month of life. Discussion: Universal screening of cCMV enables monitoring of all infected infants, identifying cases of late-onset/progressive hearing loss sooner; but in the presence of an unknown cause- sensorineural hearing loss from the first two weeks of life, efforts must be made to rule out cCMV infection, although it is more complicated under these conditions. Conclusion: The inclusion of cCMV diagnosis into neonatal hearing screening program, will allow early detection of congenital infection in some infants, improving their quality of life. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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