| Autor: |
Korhan İPEKKAN, Çiğdem ATAMAN HATİPOĞLU, Behiç ORAL, Günay Tuncer ERTEM, M. Arzu YETKİN, F. Şebnem ERDİNÇ, Celal KILIÇ, Levent İNAN, Cemal BULUT, Ali Pekcan DEMİRÖZ |
| Jazyk: |
angličtina |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi, Vol 15, Iss 2, Pp 68-77 (2010) |
| Popis: |
Introduction: Catheter-related bloodstream infections (CRBSI) are considered as one of the most common serious complications associated with the use of central venous catheters (CVC). In this study, we aimed to determine the rate and epidemiological and microbiological characteristics of the CRBSIs and the effective risk factors in patients hospitalized in the neurology and neurosurgery intensive care units (ICU). Patients and Methods: This prospective study was carried out between January 2007 and January 2008. All patients hospitalized in neurology and neurosurgery ICUs with newly inserted CVC were enrolled into the study. CRBSI rate and epidemiological and microbiological characteristics and risk factors for CRBSIs were studied. Results: During the study period, 199 CVCs in 148 patients were followed. Eighty-two patients (55.4%) were female and 66 (44.6%) were male, and the mean age was 58.7 ± 21.8 years. Sixty-seven patients (45.3%) were hospitalized in the neurology ICU and 81 (54.7%) in the neurosurgery ICU. Mean hospital stay in the ICU was 15.6 ± 15.3 days. Mean duration of catheterization was 8.5 ± 5.2 days. Total catheter days were 1703. CRBSI rates were 30.25 per 1000 catheter days in the neurology ICU and 12.45 per 1000 catheter days in the neurosurgery ICU. The most commonly isolated microorganisms were methicillin-resistant coagulase negative staphylococcus (25%) and penicillin-resistant enterococcus (25%). In univariate analyses, we found that prior antibiotic therapy rate was higher (p= 0.02) and mean hospital stay in ICU was longer (p< 0.001) in patients with CRBSI compared with patients without CRBSI. In patients hospitalized in the neurology ICU, CRBSI risk was 2.4 times higher than in neurosurgery ICU patients (p= 0.004). Catheters kept in place for more than 7 days increased the risk of CRBSI 6.3 times (p< 0.001). In multivariate analyses, catheterization days and hospital stay in ICU were found to be independent risk factors (p< 0.001). Conclusion: Catheterization days and hospital stay were found to be independent risk factors for CRBSIs. We think that for patients with CVC whose catheterization day and hospital stay are prolonged, physicians should be attentive for the development of CRBSIs. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
