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Objective: To explore the influence of ginkgo leaf tablets combined with nifedipine tablets treatment on the relevant indexes of prethrombotic state in hypertension patients. Methods: A total of 80 cases with hypertension were selected, who were admitted in our hospital from May 2014 to June 2015, and all of whom was randomly divided into study group and control group (n=40). Patients in study group were given ginkgo leaf tablets combined with nifedipine tablets treatment, while patients in control group were given nifedipine tablets treatment only. The changes of blood pressure indexes between groups before and after treatment were compared. the changes of hemodynamic indexes between groups before and after treatment were analyzed. And the changes of molecular markers of prethrombotic state between groups before and after treatment were observed. Results: Before treatment, comparative difference of systolic pressure, diastolic pressure levels, hemodynamic indexes(MH, ML, MP, HCT, ESR, AI), VWF, GMP, D-dimer and PAI-1 levels between groups had no statistical significance (P>0.05); while after treatment, systolic pressure, diastolic pressure levels, hemodynamic indexes(MH, ML, MP, HCT, ESR, AI), VWF, GMP, D-dimer and PAI-1 levels in both groups were obviously lower than before treatment (P |
