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Chao Liu,1,2 Zhou Huang,1 Qiusheng Wang,1 Bing Sun,1 Lijuan Ding,1 Xiangying Meng,1 Shikai Wu1,2 1Department of Radiation Oncology, Affiliated Hospital of Academy of Military Medical Sciences, 2Department of Radiation Oncology, 307 Hospital of PLA, 307 Clinical College, Anhui Medical University, Beijing, People’s Republic of China Purpose: We aimed to investigate the relationship between pretreatment neutrophil-to-lymphocyte ratio (NLR)/platelet-to-lymphocyte ratio (PLR) and the estimation of hormone-receptor-negative (HR-) breast cancer patients’ survival in a Chinese cohort.Patients and methods: Of 434 consecutive HR- nonmetastatic breast cancer patients treated between 2004 and 2010 in the Affiliated Hospital of Academy of Military Medical Sciences, 318 eligible cases with complete data were included in the present study. Kaplan–Meier analysis was performed to determine the overall survival (OS) and disease-free survival (DFS). Univariate and multivariate Cox proportional hazards models were used to test the usefulness of NLR and PLR.Results: Univariate analysis indicated that both elevated NLR and PLR (both P |